Research line:

Neural and endocrine secretory pathways in normal and pathological conditions.

• Studies on biogenesis, trafficking and exocytosis of secretory organelles and excitation-secretion coupling.
• Identification of alteration of secretory processes in neural and endocrine cells in human diseases.
• Identification of new brain biomarkers for human diseases.

Capacities

• Disease / disorder characterization: Cellular and molecular alterations
• Assessment of new treatments: Animal models
• Methods for diagnostic: Brain and cerebrospinal fluid analysis in mice and humans
• In vitro models: Primary cultures and cell lines
• In vivo models: Normal and genetically modified mice
• Development of new tools / technologies / computational methods: Biochemical and imaging secretion assays

Keywords: secretion, Alzheimer, calcium, cerebrospinal fluid, exocytosis, biomarker.

Contact

Dr. Fernando Aguado

faguado (at) ub.edu