Seminar – Dr. Juan L. Gomez – “Negative feedback neuromodulation: A novel cocaine-sensitive chemogenetic receptor”

Chemical feedback plays a central role in addiction, yet selectively modulating drug-induced brain signaling without altering normal function remains a major challenge. This talk will present a new chemogenetic strategy using engineered cocaine-gated ion channels to reduce cocaine reinforcement, integrating Positron Emission Tomography and chemogenetics to reveal new therapeutic opportunities.

Dr. Juan Gomez is currently a Staff Scientist at the National Institute on Drug Abuse (NIDA). His work focuses on utilizing radiometric approaches through PET imaging and autoradiography to uncover new insights into brain function and behavior.

Faculty of Medicine and Health Sciences (Bellvitge Campus), University of Barcelona