Unleashing neural lineage plasticity for neuronal reprogramming in the adult brain”

Dr. Gascón is a prominent figure in neuronal reprogramming and current group leader at the Cajal Institute (CSIC) in Madrid. Early in his career, Dr. Gascón spent a formative period at the prestigious laboratory of Prof. Magdalena Götz in Munich, Germany. During that time, he played a key role in pioneering protocols to convert postnatal astroglia into functional neurons—a breakthrough detailed in Nature Protocols co-authored with Götz’s team. During the talk, Dr. Gascón will explore how differentiated brain cells can break free from their lineage constraints. He’ll delve into cutting-edge molecular strategies that unlock adult brain plasticity, enabling in-situ conversion of local cell types into new neurons—a powerful avenue for regeneration and repair.