A successful event organized by the PhD Committee of the Institute of Neurosciences, University of Barcelona

As part of the study, the functional magnetic resonance imaging revealed the reduced functional connectivity between the left M2 cortex and all the brain regions analysed in mice models of the disease. By applying other innovative methodologies to monitor and modulate neural activity —ontogeny, electrophysiology, photometry and chemogenetics— the team discovered that the lack of M2 cortex activity could be responsible for the altered responses in Huntington’s disease.   

Event Details

  • Date: 8 June
  • Venue: La Muriel
  • Theme:

Identifying the different alterations and functions of the M2 cortex circuitry —beyond the cortico-striatal pathway— provides data that are crucial to further analyse the symptoms of Huntington’s disease and other neurodegenerative pathologies (Parkinson’s disease, etc.). Also, a deeper understanding of the role of the superior colliculus and its neural circuits —involved in many neurological disorders such as Huntington’s— may provide new insights into delaying the onset and severity of the symptoms in motor disorders.