Mood, Anxiety and Obsessive-Compulsive and Related Disorders
Multidisciplinary research in mental health, with a particular focus on mood disorders, anxiety, and the compulsive spectrum
Principal Investigators
Carles Soriano-Mas
Associate Professor
José M. Menchón
Associate Professor
Ma. Del Pino Alonso
Lecturer
Technologies & Methods
- Clinical and neurocognitive evaluations
- Acquisition and analysis of structural and functional neuroimaging data
- Genetic and epigenetic analyses
- Neuromodulation techniques
- Cognitive-behavioral intervention techniques
- Mobile health techniques (mHealth)
Research Team
José M. Crespo
Lecturer
Cinto Segalàs
Lecturer
Eva Real
Postdoctoral Researcher
Sara Bertolín
Early Stage Researcher
Sergi López
Early Stage Researcher
Ignacio Martínez-Zalacaín
Postdoctoral Researcher
Aida de Arriba
Postdoctoral Researcher
Carla del Río
Early Stage Researcher
Ana Pamela Chavarría
Early Stage Researcher
Marta Subirà
Postdoctoral Researcher
Active Projects
New therapeutic targets in depression: the role of situational perception
Marató TV3. 202215. Marta Subirà.
Prospective study of biomarkers and clinical predictors of long-term evolution and response to treatment in obsessive-compulsive disorder: the Barcelona cohort (B-OCDC)
Marató TV3. 202201 30 31 32 33. Ma. Del Pino, Carles Soriano-Mas.
Evolución a largo plazo, respuesta a tratamiento y recaídas de los trastornos de la compulsividad: biomarcadores neuroinflamatorios, neuropsicológicos y de neuroimagen
Carlos III Health Institute. PI22/00956. José M. Menchón.
Biomarcadores multiómicos periféricos predictores de la evolución a largo plazo del Trastorno Obsesivo-Compulsivo: la cohorte TOC Barcelona (OCD-BC)
Carlos III Health Institute. PI22/00752. Ma. Del Pino Alonso.
Habits and Obsessive-Compulsive Disorder: A Neurogenetic Perspective
Ministry of Science and Innovation. PID2022-139081OB-C22. Carles Soriano-Mas.
Selected publications
Alemany-Navarro, M., Tubío-Fungueiriño, M., Diz-de Almeida, S., Cruz, R., Lombroso, A., Real, E., Soria, V., Bertolín, S., Fernández-Prieto, M., Alonso, P., Menchón, J. M., Carracedo, A., & Segalàs, C. (2023). The genomics of visuospatial neurocognition in obsessive-compulsive disorder: A preliminary GWAS. Journal of Affective Disorders, 333, 365–376. https://doi.org/10.1016/j.jad.2023.04.060
Baenas, I., Miranda-Olivos, R., Granero, R., Solé-Morata, N., Sánchez, I., Pastor, A., del Pino-Gutiérrez, A., Codina, E., Tinahones, F. J., Fernández-Formoso, J. A., Vilarrasa, N., Guerrero-Pérez, F., Lopez-Urdiales, R., Virgili, N., Soriano-Mas, C., Jiménez-Murcia, S., de la Torre, R., & Fernández-Aranda, F. (2023). Association of anandamide and 2-arachidonoylglycerol concentrations with clinical features and body mass index in eating disorders and obesity. European Psychiatry, 66(1), e49. https://doi.org/10.1192/j.eurpsy.2023.2411
Bertolín, S., Alonso, P., Martínez-Zalacaín, I., Menchón, J. M., Jimenez-Murcia, S., Baker, J. T., Bargalló, N., Batistuzzo, M. C., Boedhoe, P. S. W., Brennan, B. P., Feusner, J. D., Fitzgerald, K. D., Fontaine, M., Hansen, B., Hirano, Y., Hoexter, M. Q., Huyser, C., Jahanshad, N., Jaspers-Fayer, F., … Tang, J. (2023). Right Prefrontal Cortical Thickness Is Associated With Response to Cognitive-Behavioral Therapy in Children With Obsessive-Compulsive Disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 62(4), 403–414. https://doi.org/10.1016/j.jaac.2022.07.865
Blanken, M. A. J. T., Oudega, M. L., Hoogendoorn, A. W., Sonnenberg, C. S., Rhebergen, D., Klumpers, U. M. H., Van Diermen, L., Birkenhager, T., Schrijvers, D., Redlich, R., Dannlowski, U., Heindel, W., Coenjaerts, M., Nordanskog, P., Oltedal, L., Kessler, U., Frid, L. M., Takamiya, A., Kishimoto, T., … Dols, A. (2023). Sex-specifics of ECT outcome. Journal of Affective Disorders, 326, 243–248. https://doi.org/10.1016/j.jad.2022.12.144
Bruin, W. B., Abe, Y., Alonso, P., Anticevic, A., Backhausen, L. L., Balachander, S., Bargallo, N., Batistuzzo, M. C., Benedetti, F., Bertolin Triquell, S., Brem, S., Calesella, F., Couto, B., Denys, D. A. J. P., Echevarria, M. A. N., Eng, G. K., Ferreira, S., Feusner, J. D., Grazioplene, R. G., … van Wingen, G. A. (2023). The functional connectome in obsessive-compulsive disorder: resting-state mega-analysis and machine learning classification for the ENIGMA-OCD consortium. Molecular Psychiatry, 28(10), 4307–4319. https://doi.org/10.1038/s41380-023-02077-0
Cano, M., Lee, E., Polanco, C., Barbour, T., Ellard, K. K., Andreou, B., Uribe, S., Henry, M. E., Seiner, S., Cardoner, N., Soriano-Mas, C., & Camprodon, J. A. (2023). Brain volumetric correlates of electroconvulsive therapy versus transcranial magnetic stimulation for treatment-resistant depression. Journal of Affective Disorders, 333, 140–146. https://doi.org/10.1016/j.jad.2023.03.093
Duran-Castells, C., Llano, A., Kawana-Tachikawa, A., Prats, A., Martinez-Zalacain, I., Kobayashi-Ishihara, M., Oriol-Tordera, B., Peña, R., Gálvez, C., Silva-Arrieta, S., Clotet, B., Riveira-Muñoz, E., Ballana, E., Prado, J. G., Martinez-Picado, J., Sanchez, J., Mothe, B., Hartigan-O’Connor, D., Wyss-Coray, T., … Ruiz-Riol, M. (2023). Sirtuin-2, NAD-Dependent Deacetylase, Is a New Potential Therapeutic Target for HIV-1 Infection and HIV-Related Neurological Dysfunction. Journal of Virology, 97(2). https://doi.org/10.1128/jvi.01655-22
Maturana‐Quijada, P., Steward, T., Vilarrasa, N., Miranda‐Olivos, R., Jiménez‐Murcia, S., Carey, H. J., Fernández‐Formoso, J., Guerrero‐Perez, F., Sánchez, I., Custal, N., Virgili, N., Lopez‐Urdiales, R., Soriano‐Mas, C., & Fernandez‐Aranda, F. (2023). Dynamic fronto‐amygdalar interactions underlying emotion‐regulation deficits in women at higher weight. Obesity, 31(9), 2283–2293. https://doi.org/10.1002/oby.23830
Miranda-Olivos, R., Baenas, I., Steward, T., Granero, R., Pastor, A., Sánchez, I., Juaneda-Seguí, A., del Pino-Gutiérrez, A., Fernández-Formoso, J. A., Vilarrasa, N., Guerrero-Pérez, F., Virgili, N., López-Urdiales, R., Jiménez-Murcia, S., de la Torre, R., Soriano-Mas, C., & Fernández-Aranda, F. (2023). Exploring the influence of circulating endocannabinoids and nucleus accumbens functional connectivity on anorexia nervosa severity. Molecular Psychiatry, 28(11), 4793–4800. https://doi.org/10.1038/s41380-023-02253-2
Picó-Pérez, M., Fullana, M. A., Albajes-Eizagirre, A., Vega, D., Marco-Pallarés, J., Vilar, A., Chamorro, J., Felmingham, K. L., Harrison, B. J., Radua, J., & Soriano-Mas, C. (2023). Neural predictors of cognitive-behavior therapy outcome in anxiety-related disorders: a meta-analysis of task-based fMRI studies. Psychological Medicine, 53(8), 3387–3395. https://doi.org/10.1017/S0033291721005444
Saiz-Masvidal, C., Contreras, F., Soriano-Mas, C., Mezquida, G., Díaz-Caneja, C. M., Vieta, E., Amoretti, S., Lobo, A., González-Pinto, A., Janssen, J., Sagué-Vilavella, M., Castro-Fornieles, J., Bergé, D., Bioque, M., Lois, N. G., Parellada, M., Bernardo, M., García-Rizo, C., González-Díaz, J. M., … Salvador, R. (2023). Structural covariance predictors of clinical improvement at 2-year follow-up in first-episode psychosis. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 120, 110645. https://doi.org/10.1016/j.pnpbp.2022.110645
Segal, A., Parkes, L., Aquino, K., Kia, S. M., Wolfers, T., Franke, B., Hoogman, M., Beckmann, C. F., Westlye, L. T., Andreassen, O. A., Zalesky, A., Harrison, B. J., Davey, C. G., Soriano-Mas, C., Cardoner, N., Tiego, J., Yücel, M., Braganza, L., Suo, C., … Fornito, A. (2023). Regional, circuit and network heterogeneity of brain abnormalities in psychiatric disorders. Nature Neuroscience, 26(9), 1613–1629. https://doi.org/10.1038/s41593-023-01404-6
Suñol, M., Alemany, S., Bustamante, M., Diez, I., Contreras-Rodríguez, O., Laudo, B., Macià, D., Martínez-Vilavella, G., Martínez-Zalacaín, I., Menchón, J. M., Pujol, J., Sunyer, J., Sepulcre, J., & Soriano-Mas, C. (2022). Neurogenetics of Dynamic Connectivity Patterns Associated With Obsessive-Compulsive Symptoms in Healthy Children. Biological Psychiatry Global Open Science, 2(4), 411–420. https://doi.org/10.1016/j.bpsgos.2021.11.009
van Roessel, P. J., Grassi, G., Aboujaoude, E. N., Menchón, J. M., Van Ameringen, M., & Rodríguez, C. I. (2023). Treatment-resistant OCD: Pharmacotherapies in adults. Comprehensive Psychiatry, 120, 152352. https://doi.org/10.1016/j.comppsych.2022.152352
Vismara, M., Benatti, B., Fineberg, N. A., Hollander, E., Van Ameringen, M., Menchon, J. M., Zohar, J., & Dell’Osso, B. (2023). Lessons from a multicenter, international, large sample size analysis of patients with obsessive–compulsive disorders: an overview of the ICOCS Snapshot studies. CNS Spectrums, 1–9. https://doi.org/10.1017/S1092852923002432