Research line

Molecular mechanisms of neuroinflammation in neurodegenerative diseases.

• Identification of pathophysiological processes present in neurological disorders such as stroke, Alzheimer’s disease or amyotrophic lateral sclerosis (ALS).
• Molecular and cellular mechanisms of neuroinflammation in neurodegenerative diseases.
• Identification of new therapeutic targets for ALS.

Capacities

• Disease / disorder characterization: ALS, Alzheimer’s disease
• Treatment discovery: Animal models and cell cultures
• Assessment of new treatments: Animal models and cell cultures
• In vitro models: Glial & neuronal primary cultures and cell lines
• In vivo models: ALS transgenic mice, stereotaxic injection
• Others: Massive sequence analysis

Keywords: neuroinflammation, translational research, neurodegeration, neuroprotection, drug discovery, animal models.

Contact

Dr. Nicole Mahy

nmahy (at) ub.edu