Dr. Sílvia Ginés Padrós

Research line

Huntington´s disease: toward an understanding of pathological mechanisms involved in cognitive and psychiatric symptoms.

 

Identification of new pharmacological targets to ameliorate or prevent the most important clinical hallmarks in HD:  Motor, cognitive and emotional disturbances.

Capacities

 

  • Disease / disorder characterization: Behaviour (motor, cognition, emotional)
  • Assessment of new treatments: In vivo and in vitro analysis of cell death, biochemical parameters, synaptic function, behaviour
  • In vitro models: Neuronal striatal cell lines
  • In vivo models: Huntington´s disease mouse models

 

Keywords: synaptic plasticity deficits, neuroprotection, long-term memory impairments, depression, p75/TrkB/BDNF, Cdk5.

Contact

 

Dr. Sílvia Ginés Padrós

silviagines (at) ub.edu

Date

August 2, 2016

Tags
cognition, depression, Huntington's disease, memory, molecular target, neurodegeneration, neuroprotection