Research Interest

This programme focuses on how a person’s cognition and behaviour are related to the brain and the rest of the nervous system. We develop experimental and clinical studies that seek to characterise functional and structural networks to understand how brain functions affect behaviour and cognition. We are also interested in the effectiveness of interventions and treatments (e.g., phonological remediation, physical exercise, cognitive training) for improving cognitive functions, daily functioning, or quality of life.

With neuropsychology at the core, the programme investigates these phenomena in the health continuum, from healthy people to a wide range of disorders or altered health conditions (e.g., cerebral palsy, cerebrovascular diseases, dual diagnosis, learning difficulties, mild cognitive impairment, obesity) combining different methods (e.g., biomarkers, medical records, neuroimaging, neuropsychological scales, non-invasive brain stimulation).

Technologies & Methods

• MRI-related data analyses software and procedures (SPM, fsl, freesurfer, matlab)
• Neuronavigated transcranial magnetic stimulation (TMS) coupled with imaging data
• Transcranial direct current stimulation for behavioural studies and coupled with fMRI acquisitions
• Integrated ambulatory recording system of circadian rhythm (Kronowise KW5)
• Neuropsychological assessment
• Structural neuroimaging analysis
• Functional neuroimaging analysis
• Magnetic resonance imaging

Active Projects

• • Ajut per incentivar i consolidar la recerca d’excel·lència ja existent a les universitats públiques de Catalunya. Programa ICREA Academia 2018. Fundació Institució Catalana de Recerca i Estudis Avançats. Maria Mataro.

• • Ajut per incentivar i consolidar la recerca d’excel·lència ja existent a les universitats públiques de Catalunya. Programa ICREA Academia 2019. Fundació Institució Catalana de Recerca i Estudis Avançats. David Bartres.

• • Caracterización de la adicción y la patologia dual. Eficacia de la cronoterapia coadyuvante en pacientes con respuesta parcial. Ministerio de Ciencia, Innovación y Universidades. PI. D2020-117767GB-I00. Ana Adan.

• • Characterization and modulation of brain networks to promote brain resilience for the COVID-19 pandemic. Fundació La Marató de TV3. 592/U/2021. David Bartres.

• • Conveni de col·laboració per l’execució del projecte “Barcelona Brain Health Initiative (BBHI). Fundació Privada Institut de Neurorehabilitació Guttmann. David Bartres.

• • CoviD-19 and brain: cognItion And meNtal heAlth (DIANA). Agència de Gestió d’Ajuts Universitaris i de Recerca. 2020PANDE00053. Carme Junque.

• • Efectes de teràpies combinades d’exercici, mindfulness i estimulació cognitiva en la cognició i la neuroplasticitat en pacients amb ictus isquèmic crònic. Fundació La Marató de TV3. Maria Mataro.

• • Estudio de los cambios cerebrales inducidos por estimulación cerebral no invasiva, como predictores del estado de salud cerebral futuro en personas de edad avanzada. Ministerio de Ciencia, Innovación y Universidades. RTI2018-095181-B-C21. David Bartres.

• • Guías basadas en la evidencia y consensuadas para la evaluación neuropsicológica de las personas con parálisis cerebral grave y parálisis cerebral discinética. Ministerio de Ciencia e Innovación. PID2020-117163RB-I00. Maria Del Roser Pueyo.

• • Healthy minds from 0-100 years: Optimising the use of European brain imaging cohorts (Lifebrain). European Union. SC1-PM-04-2016. 732592. David Bartres.

• • Inflamación, estrés y microbiota como mediadores entre la obesidad y el funcionamiento cerebral durante la adolescencia. Ministerio de Economia y Competitividad. PSI2017-86536-C2-1-R. Maria Angeles Jurado.

• • Multiple-level predictors of resilience during the COVID-19 pandemic. Lessons towards a precision preventive medicine. Agència de Gestió d’Ajuts Universitaris i de Recerca. 2020PANDE00043. David Bartres.

• • 5 Confidential agreements.

Selected Publications

• • Solé-Padullés, C., Bargalló, N., Salvador, R., Ruffini, G., Nitsche, M. A., Pascual-Leone, A., & Bartrés-Faz, D. (2021). Multifocal Transcranial Direct Current Stimulation Modulates Resting-State Functional Connectivity in Older Adults Depending on the Induced Current Density. Frontiers in Aging Neuroscience, 13, 725013. https://doi.org/10.3389/fnagi.2021.725013

• • Adan, A., & Torrens, M. (2021). Special Issue: Diagnosis and Management of Addiction and Other Mental Disorders (Dual Disorders). Journal of Clinical Medicine, 10(6), 1307. https://doi.org/10.3390/jcm10061307

• • Alves Braga de Oliveira, M., de Mendonça Filho, E. J., Carissimi, A., Lima Dos Santos Garay, L., Scop, M., Ruschel Bandeira, D., Gutiérrez Carvalho, F., Mathur, S., Epifano, K., Adan, A., Frey, B. N., & Hidalgo, M. P. (2021). The Revised Mood Rhythm Instrument: A Large Multicultural Psychometric Study. Journal of Clinical Medicine, 10(3), 388. https://doi.org/10.3390/jcm10030388

• • Arrona-Palacios, A., Díaz-Morales, J. F., Parra-Robledo, Z., & Adan, A. (2021). Sleep and Depressive Symptoms in the Morningness/ Eveningness-Suicidal Ideation Relationship Depend on School Shift in Mexican Adolescents. Journal of Clinical Medicine, 10(20), 4681. https://doi.org/10.3390/jcm10204681

• • Castells-Sánchez, A., Roig-Coll, F., Dacosta-Aguayo, R., Lamonja-Vicente, N., Sawicka, A. K., Torán-Monserrat, P., Pera, G., Montero-Alía, P., Heras-Tebar, A., Domènech, S., Via, M., Erickson, K. I., & Mataró, M. (2021). Exercise and Fitness Neuroprotective Effects: Molecular, Brain Volume and Psychological Correlates and Their Mediating Role in Healthy Late-Middle-Aged Women and Men. Frontiers in Aging Neuroscience, 13, 615247. https://doi.org/10.3389/fnagi.2021.615247

• • Fjell, A. M., Grydeland, H., Wang, Y., Amlien, I. K., Bartres-Faz, D., Brandmaier, A. M., Düzel, S., Elman, J., Franz, C. E., Håberg, A. K., Kietzmann, T. C., Kievit, R. A., Kremen, W. S., Krogsrud, S. K., Kühn, S., Lindenberger, U., Macía, D., Mowinckel, A. M., Nyberg, L., Panizzon, M. S., … Walhovd, K. B. (2021). The genetic organization of longitudinal subcortical volumetric change is stable throughout the lifespan. eLife, 10, e66466. https://doi.org/10.7554/eLife.66466

• • Grydeland, H., Sederevičius, D., Wang, Y., Bartrés-Faz, D., Bertram, L., Dobricic, V., Düzel, S., Ebmeier, K. P., Lindenberger, U., Nyberg, L., Pudas, S., Sexton, C. E., Solé-Padullés, C., Sørensen, Ø., Walhovd, K. B., & Fjell, A. M. (2021). Self-reported sleep relates to microstructural hippocampal decline in ß-amyloid positive Adults beyond genetic risk. Sleep, 44(11), zsab110. https://doi.org/10.1093/sleep/zsab110

• • Lamonja-Vicente, N., Dacosta-Aguayo, R., López-Olóriz, J., Prades-Senovilla, L., Roig-Coll, F., Castells-Sánchez, A., Soriano- Raya, J. J., Clemente, I., Miralbell, J., Barrios, M., López-Cancio, E., Cáceres, C., Arenillas, J. F., Millán, M., Torán, P., Pera, G., Fores, R., Alzamora, M. T., Mataró, M., & Via, M. (2021). Sex-Specific Protective Effects of APOE ε2 on Cognitive Performance. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 76(1), 41–49. https://doi.org/10.1093/gerona/glaa247

• • Nyberg, L., Magnussen, F., Lundquist, A., Baaré, W., Bartrés-Faz, D., Bertram, L., Boraxbekk, C. J., Brandmaier, A. M., Drevon, C. A., Ebmeier, K., Ghisletta, P., Henson, R. N., Junqué, C., Kievit, R., Kleemeyer, M., Knights, E., Kühn, S., Lindenberger, U., Penninx, B., Pudas, S., … Fjell, A. M. (2021). Educational attainment does not influence brain aging. Proceedings of the National Academy of Sciences of the United States of America, 118(18), e2101644118. https://doi.org/10.1073/pnas.2101644118

• • Pascual-Leone, A., & Bartres-Faz, D. (2021). Human Brain Resilience: A Call to Action. Annals of Neurology, 90(3), 336–349. https://doi.org/10.1002/ana.26157

• • Pascual-Leone, A., Cattaneo, G., Macià, D., Solana, J., Tormos, J. M., & Bartrés-Faz, D. (2021). Beware of Optimism Bias in the Context of the COVID-19 Pandemic. Annals of Neurology, 89(3), 423–425. https://doi.org/10.1002/ana.26001

• • Prat, G., Marquez-Arrico, J. E., Río-Martínez, L., Navarro, J. F., & Adan, A. (2021). Premorbid functioning in schizophrenia spectrum disorders with comorbid substance use: A systematic review. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 110, 110310. https://doi.org/10.1016/j.pnpbp.2021.110310